Epidemiology and survival of the five stages of chronic kidney disease in a systolic heart failure population
| Autor: | Dylan L Steen, Brittny Major, Patrick Trahan, Maria Carolina Delgado, Kathy Hebert, Leonardo Tamariz, Andre Dias, Lee M. Arcement, Emiliana Franco |
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| Rok vydání: | 2010 |
| Předmět: |
Male
medicine.medical_specialty Population Renal function Kaplan-Meier Estimate urologic and male genital diseases White People Risk Factors Internal medicine Diabetes mellitus Epidemiology Outpatients medicine Confidence Intervals Prevalence Humans Prospective Studies Intensive care medicine Prospective cohort study education Proportional Hazards Models education.field_of_study Ejection fraction business.industry Hispanic or Latino Middle Aged medicine.disease Louisiana female genital diseases and pregnancy complications Black or African American Heart failure Multivariate Analysis Disease Progression Florida Kidney Failure Chronic Female Cardiology and Cardiovascular Medicine business Kidney disease Glomerular Filtration Rate Heart Failure Systolic |
| Zdroj: | European journal of heart failure. 12(8) |
| ISSN: | 1879-0844 |
| Popis: | The epidemiology of the five stages of chronic kidney disease (CKD) in systolic heart failure (HF) patients has predominantly been described in hospitalized White patients, with little known about the prevalence in outpatient Blacks and Hispanics. The purpose of this study was to compare the prevalence of the five stages of CKD by race, ethnicity (Whites, Blacks, and Hispanics), and gender in an outpatient systolic HF population and also to evaluate the impact of CKD on mortality.We conducted a prospective study of 1301 patients recruited from two hospital facilities in Louisiana and Florida, USA. All patients were enrolled in a systolic HF disease management programme (HFDMP), which enrolled patients with an ejection fraction ofor =40% by echocardiography. The estimated glomerular filtration rate was calculated using the abbreviated Modification of Diet in Renal Disease Study equation. Patients were classified into five stages of CKD according to the National Kidney Foundation classification system. A total of 338 patients (26%) were found to have CKD. Patients with CKD were older, more likely to be Hispanics, to have less education, New York Heart Association class III, elevated systolic blood pressure, and diabetes. There was no statistical difference in prevalence by gender. Survival was reduced in patients with CKD.The prevalence of CKD in an outpatient systolic HFDMP is high, with over one in four patients affected. CKD patients had significantly lower survival rates compared with patients without CKD. |
| Databáze: | OpenAIRE |
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