Feasibility and Safety of Laparoscopic Right Colectomy in Oldest-Old Patients with Colon Cancer: Results of the CLIMHET Study Group
| Autor: | Ilaria Franco, Mehdi Ouaissi, Riccardo Memeo, Lise Courtot, Thibault Voron, Didier Mutter, Bertrand Le Roy, Denis Pezet, Ephrem Salamé, Francesco Brunetti, Nour Bou Saleh, Florence Canoui-Poitrine, Razvan Aprodu, Donato F. Altomare, Anne Berger, Nicola de’Angelis |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Adult
Male medicine.medical_specialty Colorectal cancer Comorbidity Disease-Free Survival Cohort Studies 03 medical and health sciences 0302 clinical medicine Risk Factors Humans Medicine Postoperative Period Propensity Score Laparoscopy Colectomy Aged Aged 80 and over medicine.diagnostic_test business.industry fungi food and beverages Length of Stay Middle Aged Oldest old medicine.disease Surgery Elective Surgical Procedures 030220 oncology & carcinogenesis Colonic Neoplasms Right Colectomy Feasibility Studies Regression Analysis Female 030211 gastroenterology & hepatology Patient Safety business |
| Zdroj: | Journal of Laparoendoscopic & Advanced Surgical Techniques. 28:1326-1333 |
| ISSN: | 1557-9034 1092-6429 |
| DOI: | 10.1089/lap.2018.0040 |
| Popis: | Laparoscopy for colorectal cancer treatment is widely accepted. However, there is no consensus as to whether or not laparoscopy can be considered the preferred treatment strategy in octogenarian and nonagenarian patients with colon cancer. The aim of this study was to compare operative and postoperative outcomes of laparoscopic right colectomy between oldest-old (≥80 years) and younger (80 years) patients with colon cancer.The study population was sampled from the CLIMHET Study Group cohort. Between January 2005 and December 2015, data were retrieved for all patients who had undergone elective laparoscopic right colectomy for colon cancer in five University Hospital centers in France (CHU of Clermont-Ferrand, Hôpital Civil of Strasbourg-IRCAD, Hôpital Henri-Mondor of Créteil, Hôpital Européen Georges Pompidou of Paris, and CHRU of Tours).Overall, 473 cancer patients were selected and analyzed. There were 156 oldest-old patients (median age: 84.1 years, range: 80-96) and 317 younger patients (median age: 67 years, range: 25-79). After adjusting based on propensity score on gender, obesity, American Society of Anesthesiologists score, smoking, arteriopathy, coronaropathy, comorbidity, and American Joint Committee on Cancer staging, no significant difference was found in operative and postoperative outcomes, except for time to resume a regular diet (3.6 days versus 3.0 days, P = .008) and length of hospital stay (12.1 days versus 9.1 days, P = .03), which were longer for oldest-old patients. Overall and disease-free survival rates were also equivalent between groups.These findings support that laparoscopic right colectomy can be safely performed in cancer patients aged 80 and older, and its outcomes are similar in oldest-old and younger patients. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|