Rhinovirus Associated With Severe Lower Respiratory Tract Infections in Children
| Autor: | Tasha Padilla, Carol A. Glaser, David Kiang, Shigeo Yagi, Erica J. Boston, Sharon Messenger, Janice K. Louie, Arup Roy-Burman, Lilly Guardia-LaBar, Ann Petru, David P. Schnurr |
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| Rok vydání: | 2009 |
| Předmět: |
Microbiology (medical)
medicine.medical_specialty Adolescent Rhinovirus Pneumonia Viral Intensive Care Units Pediatric medicine.disease_cause Polymerase Chain Reaction Intensive care Internal medicine Lower respiratory tract infection Pneumonia Mycoplasma Humans Medicine Child Picornaviridae Infections Respiratory tract infections business.industry Respiratory disease Infant Common cold medicine.disease Mycoplasma pneumoniae respiratory tract diseases Pneumonia Infectious Diseases Child Preschool Pediatrics Perinatology and Child Health Immunology Respiratory virus business |
| Zdroj: | Pediatric Infectious Disease Journal. 28:337-339 |
| ISSN: | 0891-3668 |
| DOI: | 10.1097/inf.0b013e31818ffc1b |
| Popis: | Rhinovirus is a respiratory virus most typically associated with the common cold and asthma exacerbations, and has not traditionally been considered to play a major role in severe lower respiratory tract infections (LRTIs). As part of a surveillance program for respiratory pathogens of public health importance, children consecutively admitted to intensive care for LRTI at a large tertiary children's hospital were tested with polymerase chain reaction for 11 respiratory viruses and Mycoplasma pneumoniae from February 21 to October 31, 2007; 43 cases were enrolled and rhinovirus was the most frequently detected pathogen, with 21 (49%) positive. Rhinovirus cases frequently were young (median age, 1.4 years [range, 44 days-15 years]), hospitalized for pneumonia (10; 48%), had chronic underlying illnesses (15; 71%), had abnormal chest radiographs (18; 86%), required mechanical ventilation (12; 57%), and had prolonged hospitalization (median length, 7 days [range, 1-29 days]). Coinfection with other viruses or bacteria was common (10; 47%). Rhinovirus may be associated with more severe LRTI in children than previously reported, particularly in the noninfluenza, nonrespiratory syncytial virus season. |
| Databáze: | OpenAIRE |
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