Improvements in antioxidant status after agraz consumption was associated to reductions in cardiovascular risk factors in women with metabolic syndrome

Autor:	Jacqueline Barona-Acevedo, Manuela Piedrahita-Blandón, Catalina Marín-Echeverri, Christopher N. Blesso, Vitelbina Nuñez-Rangel, Maria Luz Fernandez, Yeisson Galvis-Pérez
Rok vydání:	2021
Předmět:	Antioxidant 030309 nutrition & dietetics General Chemical Engineering medicine.medical_treatment Cardiovascular risk factors Physiology medicine.disease_cause Food processing and manufacture Industrial and Manufacturing Engineering 03 medical and health sciences 0404 agricultural biotechnology antioxidant enzymes medicine oxidative stress TX341-641 vaccinium meridionale andean berry glutathione peroxidase Consumption (economics) 0303 health sciences Nutrition. Foods and food supply business.industry catalase 04 agricultural and veterinary sciences General Chemistry TP368-456 medicine.disease superoxide dismutase 040401 food science Vaccinium meridionale total antioxidant capacity Metabolic syndrome business Oxidative stress Food Science
Zdroj:	CyTA-Journal of Food, Vol 19, Iss 1, Pp 238-246 (2021)
ISSN:	1947-6345 1947-6337
DOI:	10.1080/19476337.2021.1884606
Popis:	In this study were evaluated the effects of the chronic consumption of agraz (Vaccinium meridionale) on antioxidant status and oxidative stress markers in 40 women with metabolic syndrome (MetS) (47.2 ± 9.4 years) through a double-blind, crossover design study, in which participants consumed daily agraz or placebo during 4 weeks, separated by a 4-wk washout period. At the end of each intervention period, endogenous antioxidant enzymes activity, serum total antioxidant capacity (TAC) (ferric reducing ability of plasma [FRAP]; Oxygen Radical Absorbance Capacity [ORAC] and 2,2ʹ-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) [ABTS]), and oxidative stress markers (Oxo-2ʹ-deoxyguanosine (8-OHdG) and F2-isoprostane) were determined. Women who increased endogenous antioxidant enzymes activity and serum TAC after agraz consumption, compared to placebo, significantly reduced oxidative stress markers, total cholesterol, LDL-cholesterol (LDL-c) levels, and waist circumference, demonstrating beneficial effects in the group of women in whom antioxidant parameters increased after agraz consumption, evidencing an individual variability in response to the beverage consumed.
Databáze:	OpenAIRE
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