Seroprevalence and risk factors of human cytomegalovirus infection in the eastern Chinese population
| Autor: | Fuzhong Xue, Yabin Zhou, Xiuping Yu, Xiao-mei Zhang, Shukang Wang, Chunyan Ji, Ping Zhao, Dao-xin Ma |
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| Rok vydání: | 2009 |
| Předmět: |
Adult
Male Human cytomegalovirus China medicine.medical_specialty Adolescent Population Biology Antibodies Viral Serology Young Adult Sex Factors Risk Factors Seroepidemiologic Studies Occupational Exposure Virology Epidemiology medicine Humans Seroprevalence Risk factor education education.field_of_study Age Factors General Medicine Middle Aged medicine.disease Vaccination Socioeconomic Factors Immunoglobulin G Cytomegalovirus Infections Female Viral disease |
| Zdroj: | Archives of Virology. 154:561-564 |
| ISSN: | 1432-8798 0304-8608 |
| DOI: | 10.1007/s00705-009-0339-3 |
| Popis: | Epidemiology and clinical outcomes of human cytomegalovirus (HCMV) infection are known to vary between countries and are associated with socio-economic background. So far, few data are available from developing countries, where the overall burden of infectious diseases is frequently higher. Therefore, we analyzed the seroprevalence in a population of 3,740 individuals selected randomly from eastern China, aiming to determine the seroprevalence of and risk factors for HCMV infection. The overall seroprevalence was 48.07%, higher in the socioeconomically developing inland districts than in the developed forelands. The seroprevalence in females (54.60%) was significantly higher than that in males (41.58%) (P < 0.001). As for profession, peasants (61.54%) and doctors (68.48%) had a higher seropositive rate than members of other professions (P < 0.0001). A significant association between seroprevalence and increasing age was identified (P < 0.05). Our study might help to identify appropriate populations on which to focus for future HCMV vaccination. |
| Databáze: | OpenAIRE |
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