Cervical neuromyelitis optica with thoracic ependymoma
Autor: | Yeow Leng Tan, Minghe Moses Koh |
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Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: |
Ependymoma
medicine.medical_specialty Weakness Cord medicine.medical_treatment law.invention Lesion Intramedullary rod Aquaporin-4 antibodies law medicine Rehabilitation Neuromyelitis optica medicine.diagnostic_test business.industry Image Report Magnetic resonance imaging medicine.disease Spine Surgery Neurology (clinical) Radiology medicine.symptom business |
Zdroj: | Surgical Neurology International |
ISSN: | 2152-7806 2229-5097 |
Popis: | Background: The occurrence of cervical neuromyelitis optica (NMO) in a patient with a thoracic ependymoma is uncommon. Here, we present a patient with a spinal ependymoma who developed the new onset of NMO 2 months later. Case Description: A 66-year-old male presented with right lower limb weakness. The magnetic resonance (MR) revealed an intramedullary spinal cord tumor at the T2-T4 level. It was surgically excised and proved pathologically to be an ependymoma. 2 months later, the patient presented with an acute partial quadriparesis and a high signal intensity cord lesion at the C2-C3 level attributed to seropositive NMO (i.e. additional diagnostic studies confirmed this diagnosis). Conclusion: Patients with intramedullary thoracic ependymomas may also develop NMO resulting in recurrent/ new neurological deficits. Critical studies utilized to diagnose NMO include brain and spine MRs showing unique intramedullary brain/cord lesions, aquaporin-4 positive serology, and classical abnormal visual studies. If the diagnosis of NMO is established, multiple additional medical therapies are warranted. |
Databáze: | OpenAIRE |
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