Effect of acute inspiratory muscle exercise on blood flow of resting and exercising limbs and glucose levels in type 2 diabetes
Autor: | Franciele Ramos Figueira, Marina Axmann de Castro, Jorge Pinto Ribeiro, Beatriz D'Agord Schaan, Cristiano Fetter Antunes, Ana Paula dos Santos Corrêa |
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Jazyk: | angličtina |
Rok vydání: | 2015 |
Předmět: |
Blood Glucose
Male medicine.medical_specialty Rest Exercício Hemodynamics lcsh:Medicine Type 2 diabetes Breathing Exercises Diabetes mellitus Internal medicine medicine Humans Endothelial dysfunction lcsh:Science Reactive hyperemia Exercise Capacidade inspiratória Aged Diabetic Autonomic Neuropathy Multidisciplinary business.industry lcsh:R Extremities Blood flow Middle Aged medicine.disease Respiratory Muscles Endocrinology medicine.anatomical_structure Diabetes mellitus tipo 2 Diabetes Mellitus Type 2 Vascular resistance Cardiology Female lcsh:Q business Research Article |
Zdroj: | Repositório Institucional da UFRGS Universidade Federal do Rio Grande do Sul (UFRGS) instacron:UFRGS PLoS ONE, Vol 10, Iss 3, p e0121384 (2015) PLoS ONE |
Popis: | To evaluate the effects of inspiratory loading on blood flow of resting and exercising limbs in patients with diabetic autonomic neuropathy. Ten diabetic patients without cardiovascular autonomic neuropathy (DM), 10 patients with cardiovascular autonomic neuropathy (DM-CAN) and 10 healthy controls (C) were randomly assigned to inspiratory muscle load of 60% or 2% of maximal inspiratory pressure (PImax) for approximately 5 min, while resting calf blood flow (CBF) and exercising forearm blood flow (FBF) were measured. Reactive hyperemia was also evaluated. From the 20 diabetic patients initially allocated, 6 wore a continuous glucose monitoring system to evaluate the glucose levels during these two sessions (2%, placebo or 60%, inspiratory muscle metaboreflex). Mean age was 58 ± 8 years, and mean HbA1c, 7.8% (62 mmol/mol) (DM and DM-CAN). A PImax of 60% caused reduction of CBF in DM-CAN and DM (P |
Databáze: | OpenAIRE |
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