Identification of Naphthol Derivatives as Novel Antifeedants and Insecticides. 1

Autor:	Praveen Kumar Kalavagunta, Rajasekharreddy Pala, Narender Ravirala, Usha Rani Pathipati
Rok vydání:	2014
Předmět:	Insecticides Insecta biology Traditional medicine Chemistry Spodoptera litura Naphthols General Chemistry Spodoptera biology.organism_classification Plant Leaves Eating β naphthol Animals Bioassay General Agricultural and Biological Sciences Achaea janata
Zdroj:	Journal of Agricultural and Food Chemistry. 62:6571-6576
ISSN:	1520-5118 0021-8561
Popis:	A series of β-naphthol-derived 2-aminobenzothiazolomethylnaphthol derivatives (4a-4q) were synthesized and purified in excellent yields (86-94%) using green protocols and screened for their antifeedant and toxic activities against tobacco caterpillar (Spodoptera litura) and castor semilooper (Achaea janata) using no-choice leaf disk and topical bioassay methods. Four of them, 4d, 4f, 4i, and 4j, were identified to be potent antifeedants with ED50 values of 16.4, 19.3, 7.0, and 5.2 μg/cm(2) against S. litura and 13.9, 17.2, 10.2, and 7.7 μg/cm(2) against A. janata, respectively, and the mortality rate is95% for 4i and 4j in the case of S. litura and 4j in case of A. janata at a dosage of 0.2 μg/insect. Compounds 4d, 4i, and 4m are moderately toxic to A. janata only. Overall, this study identified a novel class of synthetic compounds that do not belong to organochlorides, organophosphates, carbamates, or neonicotinoids as strong antifeedants as well as insecticides.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::807e0d8cfb32af2fecd0e0a561760315 https://doi.org/10.1021/jf501705u Zobrazit plný text záznamu