Intravenous nicardipine in hypertensive children
| Autor: | M. Cloup, Philippe Jouvet, Philippe Hubert, Jean-Marc Treluyer, S. Couderc |
|---|---|
| Rok vydání: | 1993 |
| Předmět: |
Male
First line medicine.medical_treatment Nicardipine Blood Pressure Paediatric intensive care unit Heart rate Humans Medicine Child Infusions Intravenous Chemotherapy business.industry Paediatric intensive care Infant Newborn Infant Intensive Care Units Blood pressure Child Preschool Anesthesia Hypertension Pediatrics Perinatology and Child Health Drug Evaluation Female business medicine.drug |
| Zdroj: | European Journal of Pediatrics. 152:712-714 |
| ISSN: | 1432-1076 0340-6199 |
| DOI: | 10.1007/bf01953981 |
| Popis: | Fourteen hypertensive patients hospitalized in a paediatric intensive care unit were studied to evaluate safety and hypotensive efficacy of intravenous nicardipine. Systolic and diastolic blood pressure significantly decreased 1 h after the beginning of the treatment (1 microgram/kg per minute). Mean decrease in systolic blood pressure during the first 24 h was between 9.9% and 13.4% of the initial value. Mean lowering of diastolic blood pressure was between 16.7% and 25.6%. Nicardipine did not significantly affect heart rate with dose of 1 microgram/kg per minute. No clinical side-effects were observed. Nicardipine could be a first line drug for the treatment of hypertension in paediatric intensive care units. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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