Parasympathetic tonic dilatory influences on cerebral vessels
| Autor: | William T. Talman, Deidre Nitschke Dragon, Nicholas C. Boysen |
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| Rok vydání: | 2009 |
| Předmět: |
Male
Central nervous system Hemodynamics Article Tonic (physiology) Rats Sprague-Dawley Cellular and Molecular Neuroscience Parasympathetic nervous system Species Specificity Parasympathetic Nervous System Animals Medicine Autonomic Pathways Endocrine and Autonomic Systems business.industry Ganglia Parasympathetic Cerebral Arteries Denervation Rats Ganglion Vasodilation Facial Nerve Autonomic nervous system medicine.anatomical_structure Cerebral blood flow Cerebrovascular Circulation Anesthesia Pterygopalatine ganglion Neurology (clinical) business |
| Zdroj: | Autonomic Neuroscience. 147:101-104 |
| ISSN: | 1566-0702 |
| DOI: | 10.1016/j.autneu.2009.01.009 |
| Popis: | Parasympathetic nerves from the pterygopalatine ganglia may participate in development of cluster headaches, in vascular responses to hypertension and in modulation of damage due to stroke. Stimulation of the nerves elicits cerebral vasodilatation, but it is not known if the nerves tonically influence cerebrovascular tone. We hypothesized that parasympathetics provide a tonic vasodilator influence and tested that hypothesis by measuring cerebral blood flow in anesthetized rats before and after removal of a pterygopalatine ganglion. Ganglion removal led to reduced cerebral blood flow without changing blood pressure. Thus, parasympathetic nerves provide tonic vasodilatory input to cerebral blood vessels. |
| Databáze: | OpenAIRE |
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