The evaluation of the triglyceride glucose index in symptomatic patients with high suspicion of coronary artery disease: A single center study

Autor: Sara Cetin Sanlialp, Gökay Nar
Rok vydání: 2021
Předmět:
multivariate logistic regression analysis
Index (economics)
retrospective study
Single Center
Coronary artery disease
low density lipoprotein cholesterol
chemistry.chemical_compound
high density lipoprotein cholesterol
middle aged
Medicine
Sağlık Bilimleri ve Hizmetleri
glucose
hemoglobin A1c
Syntax i
C reactive protein
adult
creatinine
General Medicine
female
Cardiology
blood sampling
disease severity
triacylglycerol
medicine.medical_specialty
Triglyceride glucose index
Gensini score
Article
General Biochemistry
Genetics and Molecular Biology
Gensini
male
Health Care Sciences and Services
Internal medicine
left anterior descending coronary artery
follow up
Coronary artery disease
GENSINI
SYNTAX I
Triglyceride glucose index
controlled study
human
cardiovascular diseases
Triglyceride
business.industry
disease association
hemoglobin
case control study
medicine.disease
major clinical study
chemistry
observational study
coronary angiography
business
Zdroj: Volume: 38, Issue: 4 599-603
Journal of Experimental and Clinical Medicine
ISSN: 1309-5129
1309-4483
Popis: Triglyceride glucose index (TyG) plays an important role in metabolic syndrome (MetS), which predisposes to the development of cardiovascular diseases (CVD). Mostly, the association between the TyG index and coronary artery disease (CAD) has been investigated in healthy individuals on long-term follow-up or in asymptomatic patients with a mild and mild-moderate cardiovascular risk profile. However, there are few studies evaluating the association of TyG index with CAD in symptomatic patients. In hence, we aimed to determine the role of the TyG index in the presence and severity of CAD in symptomatic patients with high suspicion of CAD in this study. 100 patients who underwent coronary angiography were included and the patients were divided into two groups according to the presence of CAD. TyG index was calculated by the formula Ln [fasting triglycerides (mg/dl) fasting glucose (mg/dl)/2]. The severity of CAD was assessed by angiographic risk scores GENSINI, SYNTAX I, and the number of diseased vessels. TyG index did not differ significantly between patients with and without CAD. Also, there was no significant correlation between TyG index and GENSINI, SYNTAX I, and the number of diseased vessels. (for all p>0.05) In multiple logistic regression analysis, the only independent predictor of CAD was age. (p=0.03, OR=1.048, 95% CI=1.004-1.094) In conclusion, TyG index may not be a useful marker for predicting the presence or severity of CAD. According to the results of this study, age is the only predictor of CAD independent of all causes. © 2021 Ondokuz Mayis Universitesi. All rights reserved.
Databáze: OpenAIRE
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