Synthesis and comparative antibacterial studies of some benzylidene monosaccharide benzoates
| Autor: | Md. Manir Hossain, Mohammad M. H. Bhuiyan, Mohammed Mahbubul Matin, Mohammad Harun Or Roshid |
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| Rok vydání: | 2015 |
| Předmět: | |
| Zdroj: | Journal of the Turkish Chemical Society, Section A: Chemistry, Vol 2, Iss 4, Pp 12-21 (2015) Volume: 2, Issue: 4 12-21 Journal of the Turkish Chemical Society Section A: Chemistry |
| ISSN: | 2149-0120 |
| Popis: | Some 4,6-O-benzylidene protected 2,3-di-O-benzoates of methyl a-D-glucopyranoside and methyl a-D-mannopyranoside were prepared. All the compounds (1-7) were screened for in vitro antibacterial activity study against ten human pathogenic bacteria. The study revealed that the benzoylated mannopyranosides (5-7) are more prone towards antibacterial functionalities than that of the glucopyranosides (2-3). Metil a-D-glukopiranozid ve metil a-D-mannopiranozidin 4,6-O-benziliden ile korunmuş 2,3-di-O-benzoatları hazırlanmıştır. Bütün bileşikler (1-7) on adet insana karşı patojenik bakteriye karşı in vitro antibakteriyel aktivite çalışması için görüntülenmiştir. Çalışmaya göre, benzoillenmiş mannopiranozidler (5-7) glukopiranozidlere (2-3) karşı antibakteriyel işlevsellik bakımından daha narindir. |
| Databáze: | OpenAIRE |
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