Absence of change of signal-averaged electrocardiogram identifies patients with ventricular arrhythmias who are non-responders to amiodarone

Autor: Daniel Beurrier, Pierre Houriez, C. Suty-Selton, Béatrice Brembilla-Perrot, Olivier Claudon
Rok vydání: 2002
Předmět:
Zdroj: International Journal of Cardiology. 83:47-55
ISSN: 0167-5273
DOI: 10.1016/s0167-5273(02)00011-6
Popis: Objectives: The aim of this study was to assess the ability of a non-invasive study, the signal-averaged ECG (SAECG), to predict the effect of amiodarone at ventricular level. Background: Amiodarone is the main drug drug used in the treatment of ventricular arrhythmias. Standard ECG does not detect any change in QRS complex resulting from amiodarone therapy. SAECG is more sensitive than ECG for detecting changes in QRS complex. Methods: The study examined the effects of amiodarone on SAECG in relation to the results of programmed ventricular stimulation in 68 patients with old myocardial infarction, spontaneous and inducible sustained ventricular tachycardia (VT). Results: Amiodarone prolonged the total QRS duration (dur) (129±28 vs. 140±30 ms, P
Databáze: OpenAIRE