Isolation and characterization of 25 unique DNA markers for human chromosome 22

Autor:	Nick A. van Biezen, Ben A. Oostra, Ronald H. Lekanne Deprez, Ad Geurts van Kessel, Ellen C. Zwarthoff, Abel Thijs, Peter Heutink
Rok vydání:	1993
Předmět:	Genetics Genetic Markers Gene map Chromosomes Human Pair 22 Chromosome DNA Biology Molecular biology Cell Line chemistry.chemical_compound Gene mapping chemistry Genetic linkage Genetic marker Humans Restriction fragment length polymorphism Chromosome 22 Polymorphism Restriction Fragment Length
Zdroj:	Genomics. 15(1)
ISSN:	0888-7543
Popis:	Twenty-five single-copy anonymous DNA markers for human chromosome 22 were isolated. These markers were assigned to four different regions on the chromosome. Six markers recognize restriction fragment length polymorphisms. The relative positions of five of these polymorphic markers on the framework map of chromosome 22 were determined by linkage analysis. The sizes of the NotI fragments recognized by 22 markers were determined by pulsed-field gel analysis. The total length of the NotI fragments identified is at least 12 Mb, which represents about 20% of the entire chromosome. 15 refs., 1 fig.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f36c6462f0f2a9167b5a90fdb0c2fff https://pubmed.ncbi.nlm.nih.gov/8094368 Zobrazit plný text záznamu