Process intensification of a photochemical oxidation reaction using a Rotor-Stator Spinning Disk Reactor: A strategy for scale up
| Autor: | Raoul B.J. Hendrix, Jasper Hacking, Timothy Noël, Emma Anna Carolina Emanuelsson, Parimala Shivaprasad, Koen P. L. Kuijpers, John van der Schaaf, Arnab Chaudhuri |
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| Přispěvatelé: | Chemical Reactor Engineering, Chemical Engineering and Chemistry, Micro Flow Chemistry and Synthetic Meth., EIRES Eng. for Sustainable Energy Systems |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Pressure drop
Materials science General Chemical Engineering Mixing (process engineering) Photoredox catalysis Rotational speed 02 engineering and technology General Chemistry 010402 general chemistry 021001 nanoscience & nanotechnology Photochemistry 01 natural sciences Industrial and Manufacturing Engineering 0104 chemical sciences Volumetric flow rate Volume (thermodynamics) SCALE-UP Photocatalysis Environmental Chemistry 0210 nano-technology |
| Zdroj: | Chemical Engineering Journal, 400:125875. Elsevier |
| ISSN: | 1385-8947 |
| Popis: | Photochemical transformations have witnessed a remarkable growth of attention in the past decade due to the popularity of photoredox catalysis and the technological progress in energy-efficient light sources. However, the scaling of these photon-induced processes remains a daunting challenge for chemists and engineers in the industry, often discouraging their implementation in the production of fine chemicals and pharmaceuticals. To address this key issue, we report herein the development of a conceptually new photochemical reactor, called photo Rotor-Stator Spinning Disk Reactor. The photocatalyzed gas–liquid oxidation of α-terpinene to the drug ascaridole with Rose Bengal as photocatalyst was achieved with throughputs of over 1 kg·day−1 (270 mmol·h−1) under visible light irradiation. The performance of the reactor is correlated to various process parameters such as rotation speed, liquid flowrate, and catalyst concentration, among others. The conversion and selectivity increase from 37% to 97% and 75% to 90% respectively with an increase of rotation speed from 100 to 2000 RPM. The reactor operates with negligible pressure drop and allows for facile fine-tuning of the mixing efficiency. In this paper, we have also compared the performance of this reactor to other reactors such as the batch, micro, thin-film, and the vortex reactor, among others, and have found the photo-Rotor-Stator Spinning Disk Reactor to have superior productivity as well as higher productivity per volume (2.8 mol ·s−1 ·m−3). The findings of this study can be used to study, design, optimize and scale photochemical processes using the rotor–stator spinning disk reactor. |
| Databáze: | OpenAIRE |
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