Bipolar catheter ablation in ventricular myocardium
| Autor: | Qiushi Chen, Wenwu Zhu, Pipin Kojodjojo, Fengxiang Zhang, Baohan Fan, Hongyan Zhao, Yeqian Zhu, Xiaolin Liu, Pengcheng Zhao |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Swine Heart Ventricles medicine.medical_treatment Catheter ablation In Vitro Techniques 030204 cardiovascular system & hematology Cardiac Catheters Free wall Ventricular myocardium Lesion 03 medical and health sciences 0302 clinical medicine Catheter radiofrequency ablation Internal medicine medicine Animals 030212 general & internal medicine Therapeutic Irrigation Electrodes Saline business.industry Bipolar ablation Equipment Design General Medicine Ablation Models Animal Catheter Ablation Cardiology medicine.symptom Cardiology and Cardiovascular Medicine business |
| Zdroj: | Pacing and Clinical Electrophysiology. 43:54-61 |
| ISSN: | 1540-8159 0147-8389 |
| Popis: | BACKGROUND Recurrence rates after catheter radiofrequency ablation (RFA) for arrhythmias arising from deep myocardial substrates can exceed 40%. Failure of RFA is in part due to the inability of widely used unipolar ablation (UA) to create transmural lesions capable of disrupting the critical components of the arrhythmia circuit. A radiofrequency generator was custom-made to deliver bipolar ablation (BA) to test the hypothesis that BA is more effective compared to UA in achieving transmurality and to determine the optimal configuration for ventricular BA. METHODS Sequential UA and BA were created in porcine ventricular septal and free wall preparations using irrigated, contact-force sensing ablation catheters, orientated perpendicularly to the myocardium. Return catheters, durations of ablation, irrigating fluids, and power settings were varied to determine the optimal configuration for BA. Lesion characteristics, transmurality, and occurrence of steam pops were analyzed. RESULTS In both ventricular septal and free wall models, BA resulted in significantly more transmural lesions while causing less steam pops (P |
| Databáze: | OpenAIRE |
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