A Case of Malignant Hemangiopericytoma: An Immunohistochemical and Ultrastructural Study
| Autor: | Eishi Miyazaki, Masami Mizuki, Katsunori Sugisaki, Tomiyasu Tsuda, Tetsuro Matsumoto |
|---|---|
| Rok vydání: | 1994 |
| Předmět: |
Pulmonary and Respiratory Medicine
Pathology medicine.medical_specialty Lung Neoplasms Malignant hemangiopericytoma medicine.medical_treatment stomatognathic system medicine Humans Vimentin Hemangiopericytoma Multiple Pulmonary Nodules Chemotherapy Factor VIII Lung Brain Neoplasms business.industry Respiratory disease Antibodies Monoclonal Middle Aged medicine.disease Immunohistochemistry Submandibular Gland Neoplasms Microscopy Electron medicine.anatomical_structure Ultrastructure Female business |
| Zdroj: | Respiration. 61:172-175 |
| ISSN: | 1423-0356 0025-7931 |
| DOI: | 10.1159/000196332 |
| Popis: | We report one case of malignant hemangiopericytoma which started with a tumor in the lower jaw and multiple nodules in the lung. The tumor quickly metastasized to the brain and chemotherapy was not at all effective. Hemangiopericytoma is generally diagnosed by its histological characteristics. Recently, however, electron microscopy and immunohistochemical methods have been used for its diagnosis. In our case, electron micrograph showed the growth of hemangiopericytoma cells around immature endothelial cells. In addition, the tumor cells reacted positively only with anti-vimentin antibodies, and the endothelial cells in the tumor tissue were positive for antifactor VIII antibodies. The observed features were consistent with the characteristics of hemangiopericytoma. |
| Databáze: | OpenAIRE |
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