Proton Therapy Treatment Plan Verification in CCB Krakow Using Fred Monte Carlo TPS Tool
| Autor: | Antoni Rucinski, F. Tommasino, A. Skrzypek, E. Scifoni, G. Battistoni, Angelo Schiavi, Vincenzo Patera, M. Garbacz, Marco Durante, Nils Krah, Ilaria Rinaldi, J. Gajewski |
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| Přispěvatelé: | Institute of Nuclear Physics PAN, Krakow, Poland, Politecnico di Torino = Polytechnic of Turin (Polito), Institut de Physique Nucléaire d'Orsay (IPNO), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11), Imagerie Tomographique et Radiothérapie, Centre de Recherche en Acquisition et Traitement de l'Image pour la Santé (CREATIS), Université Jean Monnet [Saint-Étienne] (UJM)-Hospices Civils de Lyon (HCL)-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Université de Lyon-Institut National des Sciences Appliquées (INSA)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Jean Monnet [Saint-Étienne] (UJM)-Hospices Civils de Lyon (HCL)-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM), Università degli Studi di Roma 'La Sapienza' = Sapienza University [Rome], Institut de Physique Nucléaire de Lyon (IPNL), Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Trento Institute for Fundamental Physics and Applications, Italy, AGH University of Science and Technology [Krakow, PL] (AGH UST) |
| Rok vydání: | 2018 |
| Předmět: |
Computer science
business.industry Nuclear engineering Monte Carlo method Cyclotron GPU Imaging phantom Monte Carlo simulations 030218 nuclear medicine & medical imaging Pencil (optics) law.invention 03 medical and health sciences 0302 clinical medicine law 030220 oncology & carcinogenesis proton therapy [PHYS.PHYS.PHYS-MED-PH]Physics [physics]/Physics [physics]/Medical Physics [physics.med-ph] treatment planning system business Radiation treatment planning Proton therapy Quality assurance Beam (structure) |
| Zdroj: | IFMBE Proceedings ISBN: 9789811090349 World Congress on Medical Physics and Biomedical Engineering 2018 World Congress on Medical Physics and Biomedical Engineering 2018, pp.783-787, 2019, 978-981-10-9035-6. ⟨10.1007/978-981-10-9035-6_144⟩ |
| Popis: | International audience; Monte Carlo (MC) methods account for many details of the interactions of particles with human tissue in proton beam therapy. The accuracy and fast dose calculation time offered by GPU-accelerated MC treatment planning systems (TPS) pushed development of such tools to support experimental treatment plan verification in the clinical routine. The GPU-accelerated MC-TPS Fred (Schiavi et al, Phys Med Biol 62:7482, 2017, [4]; University of Rome) is currently investigated in Cyclotron Centre Bronowice (CCB) Krakow proton beam therapy centre (Poland) that is in clinical operation from October 2016. The Krakow proton centre physical beam model has been implemented in Fred and was validated against Eclipse TPS calculations and patient Quality Assurance (QA) measurements in water phantom. We analyzed depth-dose distributions of single proton pencil beams and dose cubes of varying range and modulation in water. We used the gamma index method as quantitative measure and obtained a good agreement between Fred and analytical TPS calculations. We have also found that Fred reach proton tracking rates over $$ 10^{6} $$ primaries per second. In the future, the proposed fast MC methods can help to reduce the time needed for experimental patient treatment plan verification measurements in water phantoms that are part of clinical routine procedures. |
| Databáze: | OpenAIRE |
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