Impact of Cranberry Juice Enriched with Omega-3 Fatty Acids Adjunct with Nonsurgical Periodontal Treatment on Metabolic Control and Periodontal Status in Type 2 Patients with Diabetes with Periodontal Disease
| Autor: | Ahmad Zare Javid, Elnaz Ashrafzadeh, Maryam Ravanbakhsh, Mehrnoosh Zakerkish, Hosein Babaei, Leila Maghsoumi-Norouzabad, Hojat allah Yousefimanesh, Kambiz Ahmadi Angali |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Adult Blood Glucose Male medicine.medical_specialty Medicine (miscellaneous) 030209 endocrinology & metabolism Type 2 diabetes Gastroenterology law.invention 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine food Randomized controlled trial law Diabetes mellitus Internal medicine Fatty Acids Omega-3 Medicine Humans food.beverage Periodontal Diseases Glycemic Aged Glycated Hemoglobin 030109 nutrition & dietetics Nutrition and Dietetics medicine.diagnostic_test business.industry CRANBERRY JUICE Type 2 Diabetes Mellitus Middle Aged medicine.disease Fruit and Vegetable Juices Vaccinium macrocarpon chemistry Diabetes Mellitus Type 2 Female Glycated hemoglobin business Lipid profile |
| Zdroj: | Journal of the American College of Nutrition. 37(1) |
| ISSN: | 1541-1087 |
| Popis: | Objectives Cranberries, high in polyphenols, have been associated with a favorable glycemic response in patients with type 2 diabetes and also are beneficial for oral health. Because type 2 diabetes mellitus and periodontal disease have a physiological relationship, this study aimed to evaluate the hypothesis that cranberry juice enriched with omega-3 will improve glycemic and lipid profiles and periodontal status in patients with diabetes with periodontal disease. Materials and methods In this randomized clinical trial, 41 patients with diabetes (age 35-67 years) with periodontal disease were recruited and randomly assigned to 4 groups: control (C; n = 12), receiving omega-3 (I1; n = 10, 1 g/ twice daily), cranberry juice (I2; n = 9, 200 ml, twice daily), and cranberry juice enriched with omega-3 (I3; n = 10, 200 ml, containing 1 g omega-3) twice daily for 8 weeks. Nonsurgical periodontal therapy was provided for all patients during the study. Fasting blood glucose and glycated hemoglobin, lipid profile, probing depth, anthropometric indices, and 3-day 24-hour dietary recalls were measured pre- and postintervention. Results Glycated hemoglobin was decreased significantly in I1 and I3 groups. Serum high-density lipoprotein cholesterol (HDL-C) levels increased significantly in the I3 group compared to baseline and compared to I1 and I2 groups. Probing depth was significantly reduced in all groups postintervention. Conclusion Consumption of cranberry juice enriched with omega-3 can be beneficial as adjuvant therapy with nonsurgical periodontal therapy in decreasing glycated hemoglobin, increasing HDL-C, and improving periodontal status in patients with diabetes with periodontal disease. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|