In vitro studies on lymphocyte Fcγ receptor blocking factors in human renal transplantation
| Autor: | M. A. Mcmillan, J. D. Briggs, B. J. R. Junor, R.N.M. Macsween, J. Highet, D. Degiannis, G.P. Sandilands |
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| Rok vydání: | 1990 |
| Předmět: |
Rosette Formation
Lymphocyte Immunology Receptors Fc In Vitro Techniques Lymphocyte Activation Biological Factors Cell surface receptor medicine Humans Immunology and Allergy Receptor B cell B-Lymphocytes Kidney biology Graft Survival Antibodies Monoclonal Blood Proteins Kidney Transplantation In vitro Transplantation medicine.anatomical_structure Immunoglobulin G biology.protein Mitogens Antibody |
| Zdroj: | Immunology Letters. 26:153-157 |
| ISSN: | 0165-2478 |
| Popis: | In this study we have confirmed our earlier observation that the presence in pre-transplant serum of a high-molecular-weight lymphocyte Fcγ receptor blocking factor correlates with improved human renal allograft survival. This factor was found to bind preferentially to B cells and to impair B cell function in vitro. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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