Laser polarization-variable autofluorescence of the network of optically anisotropic biological tissues: Diagnostics and differentiation of early stages of cancer of cervix uteri
| Autor: | N. Pashkovskaia, D. R. Andreichuk, G. D. Koval, Yu. A. Ushenko, Yu. F. Marchuk, M. I. Sidor |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Pathology
medicine.medical_specialty Materials science Biomedical Engineering Medicine (miscellaneous) lcsh:Technology law.invention Microinvasive carcinoma Laser polarization law medicine diagnostics lcsh:QC350-467 Cervix polarization Birefringence birefringence lcsh:T medical and autofluorescence imaging statistical optics Endometrium biopsy medicine.disease Laser Atomic and Molecular Physics and Optics Electronic Optical and Magnetic Materials Autofluorescence medicine.anatomical_structure Dysplasia lcsh:Optics. Light |
| Zdroj: | Journal of Innovative Optical Health Sciences, Vol 7, Iss 3, Pp 1450024-1-1450024-10 (2014) |
| ISSN: | 1793-7205 1793-5458 |
| DOI: | 10.1142/S1793545814500242 |
| Popis: | This research presents the results of investigation of laser polarization fluorescence of biological layers (histological sections, cytological smears) in the task of diagnostics and differentiation of early stages of cancer: Dysplasia — cervical microinvasive carcinoma of cervix uteri. The analytical conditions of polarization-optimal probing of biological layers were determined basing on the model of linear birefringence and dichroism of birefringent (fibrillar, porphyrin) networks. The technique of polarization-variable laser autofluorescence was developed and experimentally tested. The objective criteria (statistical moments) of differentiation of histological sections autofluorescent images of endometrium biopsy and cytological smears of it mucous coat were defined. The operational characteristics (sensitivity, specificity, accuracy) of this technique were determined concerning the positions of probative medicine, and clinical efficiency. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|