Relationship between 90-kilodalton heat shock protein, estrogen receptor, and progesterone receptor in human mammary tumors
| Autor: | S. J. Ullrich, Gopalan Shyamala, M. Schweitzer |
|---|---|
| Rok vydání: | 1993 |
| Předmět: |
Cancer Research
medicine.medical_specialty medicine.drug_class Chemistry Estrogen receptor Breast Neoplasms Hsp70 Kilodalton Endocrinology Oncology Receptors Estrogen Estrogen Internal medicine Heat shock protein Progesterone receptor medicine Humans Female Receptors Progesterone Estrogen receptor alpha Estrogen receptor beta Heat-Shock Proteins |
| Zdroj: | Breast cancer research and treatment. 26(1) |
| ISSN: | 0167-6806 |
| Popis: | To determine, if, as previously observed with rodent uterus, the 90 kilodalton heat shock protein (HSP-90) might be under estrogenic regulation in human mammary tumors, we analyzed its relationship with estrogen and progesterone receptors. A positive relationship between estrogen receptor and HSP-90 was observed when these were normalized to HSP-70 levels (to normalize for the intrinsic variations in each tumor, independent of any hormonal dependence). |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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