Generation, Coordination, and Evolution of Neural Circuits for Vocal Communication
| Autor: | Irene H. Ballagh, Emilie C. Perez, Ian C. Hall, Elizabeth C. Leininger, Ayako Yamaguchi, Young Mi Kwon, Darcy B. Kelley, Avelyne S. Villain, Erik Zornik, Taffeta M. Elliott, Ben J. Evans, Heather J. Rhodes, Andres Bendesky, Charlotte L. Barkan, Ursula Kwong-Brown |
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| Rok vydání: | 2020 |
| Předmět: |
Male
0301 basic medicine Larynx Xenopus Hindbrain Sensory system In Vitro Techniques Sexual Behavior Animal Xenopus laevis 03 medical and health sciences 0302 clinical medicine Species Specificity otorhinolaryngologic diseases medicine Biological neural network Animals Gonadal Steroid Hormones Social Behavior Medulla Oblongata Neurotransmitter Agents Sex Characteristics biology General Neuroscience Laryngeal Nerves Central pattern generator biology.organism_classification Biological Evolution Viewpoints Animal Communication Rhombencephalon 030104 developmental biology medicine.anatomical_structure Acoustic Stimulation Forebrain Central Pattern Generators Female Laryngeal Muscles Nerve Net Vocalization Animal Neuroscience 030217 neurology & neurosurgery Arytenoid Cartilage Social behavior |
| Zdroj: | J Neurosci |
| ISSN: | 1529-2401 0270-6474 |
| DOI: | 10.1523/jneurosci.0736-19.2019 |
| Popis: | In many species, vocal communication is essential for coordinating social behaviors including courtship, mating, parenting, rivalry, and alarm signaling. Effective communication requires accurate production, detection, and classification of signals, as well as selection of socially appropriate responses. Understanding how signals are generated and how acoustic signals are perceived is key to understanding the neurobiology of social behaviors. Here we review our long-standing research program focused onXenopus, a frog genus which has provided valuable insights into the mechanisms and evolution of vertebrate social behaviors. InXenopus laevis, vocal signals differ between the sexes, through development, and across the genus, reflecting evolutionary divergence in sensory and motor circuits that can be interrogated mechanistically. Using twoex vivopreparations, the isolated brain and vocal organ, we have identified essential components of the vocal production system: the sexually differentiated larynx at the periphery, and the hindbrain vocal central pattern generator (CPG) centrally, that produce sex- and species-characteristic sound pulse frequencies and temporal patterns, respectively. Within the hindbrain, we have described how intrinsic membrane properties of neurons in the vocal CPG generate species-specific vocal patterns, how vocal nuclei are connected to generate vocal patterns, as well as the roles of neurotransmitters and neuromodulators in activating the circuit. For sensorimotor integration, we identified a key forebrain node that links auditory and vocal production circuits to match socially appropriate vocal responses to acoustic features of male and female calls. The availability of a well supported phylogeny as well as reference genomes from several species now support analysis of the genetic architecture and the evolutionary divergence of neural circuits for vocal communication.Xenopusthus provides a vertebrate model in which to study vocal communication at many levels, from physiology, to behavior, and from development to evolution. As one of the most comprehensively studied phylogenetic groups within vertebrate vocal communication systems,Xenopusprovides insights that can inform social communication across phyla. |
| Databáze: | OpenAIRE |
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