The Influences of Whole Brain Radiotherapy on Social Cognition and Association with Hippocampal and Frontal Dosimetry
Autor: | Murat Emul, Fagan Zakirov, Funda Engin Akcam, Erhan Yuksek, Ahmet Yassa, Seda Eroz, Dilara Akturk |
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Rok vydání: | 2015 |
Předmět: |
Male
medicine.medical_specialty Tomography Scanners X-Ray Computed Emotions Hippocampus Neuropsychological Tests Audiology Statistics Nonparametric Developmental psychology Social cognition Mental process medicine Humans Karnofsky Performance Status Social Behavior Depression (differential diagnoses) Brain Neoplasms Dose-Response Relationship Radiation Recognition Psychology Cognition Middle Aged Magnetic Resonance Imaging Social relation Frontal Lobe Facial Expression Psychiatry and Mental health Anxiety Female Cranial Irradiation medicine.symptom Psychology Neurocognitive |
Zdroj: | Psychiatric Quarterly. 86:533-543 |
ISSN: | 1573-6709 0033-2720 |
Popis: | The influence of brain radiotherapy on neurocognition is a major concern. Social cognition is a mental process in the meaning of social interaction and the recognition of facial emotion is a domain of social cognition. Thus, we aimed to investigate the early effect of whole brain radiotherapy on facial emotion recognition ability. Thirteen patients with various brain tumors in the study. Beck depression and anxiety inventory and the facial emotion recognition test by using a set of photographs were performed at the beginning and post radiotherapy. The severity of depression (16.40 ± 12.16 vs 04.00 ± 02.38 points) and anxiety (14.47 ± 11.96 vs 04.54 ± 03.30 points) were significantly higher in patients. The only significance according to facial emotion recognition rate between initial phase of patients and healthy controls was identifying neutral facial em otion (p = 0.002). The patients after brain radiotherapy had significantly better rate of recognizing fear facial emotions (p = 0.039). This study is the first that investigated the effects of cranial irradiation on facial emotion recognition ability and compares this ability with healthy controls. Interestingly, in the early phase the patients seem to be improved in fear facial emotion after brain radiotherapy without sparing cognition specific regions as hippocampus and frontal regions. |
Databáze: | OpenAIRE |
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