| Přispěvatelé: |
Tammaro, Vincenzo, Carlomagno, Nicola, Santangelo, Michele, Calogero, Armando, Dodaro, Concetta A, Vernillo, Antonio, Sica, Antonello, Peluso, Gaia, Campanile, Silvia, Sagnelli, Evangelista, Sagnelli, Caterina |
| Popis: |
Background: More than 50% of patients with Colorectal cancer (CRC) present or develop hepatic metastases (HM). The intraoperative use of the Habib 4X® radio frequency probe device is safe in resetting HM and allows a one-stage resection of both CRC and HM with a similar mortality rate than a two-stage surgical treatment. Methods: After an exhaustive residential training at the reference center for hepato-biliary surgery of the Imperial College of London, we treated at our unit of general surgery 40 consecutive patients with CRC and HM with the one-stage resection, using the Habib 4X® intraoperative radiofrequency probe device to reset HM. Results: None of the 40 patients died during the intra-operatory and post-operatory periods, none presented liver failures during the postoperative course nor complication related to the Habib's resection procedure (e.g. bleeding, abscess, bile leak). The amount of intra-operative liver bleeding was minimal. New HM arose in 10 (25%) cases, with a mean disease-free interval of 13 months, but the hepatic tissue close to previous resections remained cancer-free. The 69.7 % of patients were disease-free at month 24 of the post-operative follow-up and 5-year rate was about 70%. Conclusions: The data suggest that surgeons well trained at a reference center for hepato-biliary surgery may perform with excellent results the one-stage CRC and HM resection with the Habib 4X® device even in a unit of general surgery. |
