Carcinosarcoma of the uterus: a clinicopathological multicenter CTF study
| Autor: | Paolo Zola, Enrico Sartori, Fabio Landoni, Luca Bazzurini, Andrea Lissoni, Angiolo Gadducci, Beniamino La Face, Tiziano Maggino |
|---|---|
| Přispěvatelé: | Sartori, E, Bazzurini, L, Gadducci, A, Landoni, F, Lissoni, A, Maggino, T, Zola, P, La Face, B |
| Jazyk: | angličtina |
| Rok vydání: | 1997 |
| Předmět: |
Adult
Oncology medicine.medical_specialty Prognosi MED/40 - GINECOLOGIA E OSTETRICIA Uterus Disease-Free Survival Carcinosarcoma Retrospective Studie Internal medicine Uterine Neoplasm medicine Humans Doxorubicin Neoplasm Metastasis Stage (cooking) Pathological Survival analysis Aged Neoplasm Staging Retrospective Studies Aged 80 and over Cisplatin Gynecology business.industry Obstetrics and Gynecology Retrospective cohort study General Medicine Middle Aged Prognosis medicine.disease Combined Modality Therapy Surgery Neoplasm Metastasi Lymphatic system medicine.anatomical_structure Chemotherapy Adjuvant Uterine Neoplasms Histopathology Female Radiotherapy Adjuvant Sarcoma Neoplasm Recurrence Local business Human medicine.drug |
| Popis: | The purpose of this paper is to retrospectively analyze the clinical and pathological data of 118 cases of uterine carcinosarcoma. Prognostic factors and management were evaluated. chi 2 and log-rank tests were performed. Surgical stage at time of surgery was the most important prognostic factor (P < 0.0001); in stage I-II disease depth of myometrial invasion and lymphatic/vascular space involvement were significantly related to outcome, whereas other factors were not useful. In stage I-II patients postoperative radiation did not improve 5-year disease-free survival. Survival curves in patients with advanced disease treated with cisplatin-containing regimens or with doxorubicin (without cisplatin)-containing regimens were overlapping. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|