Unaltered EEG spectral power and functional connectivity in REM microstates in frequent nightmare recallers: are nightmares really a REM parasomnia?
| Autor: | Péter Simor, Gwen van der Wijk, Borbála Blaskovich, Yeganeh Farahzadi |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Nightmare disorder Polysomnography Sleep REM REM Sleep Behavior Disorder Audiology Electroencephalography Non-rapid eye movement sleep Tonic (physiology) 03 medical and health sciences 0302 clinical medicine mental disorders medicine Humans medicine.diagnostic_test business.industry musculoskeletal neural and ocular physiology Functional connectivity General Medicine Parasomnia medicine.disease Phase lag Dreams Nightmare 030228 respiratory system medicine.symptom business psychological phenomena and processes 030217 neurology & neurosurgery |
| Zdroj: | Sleep Medicine. 75:192-200 |
| ISSN: | 1389-9457 |
| DOI: | 10.1016/j.sleep.2020.07.014 |
| Popis: | Background Frequent nightmares show signs of hyperarousal in NREM sleep. Nevertheless, idiopathic nightmare disorder is considered a REM parasomnia, but the pathophysiology of REM sleep in relation to frequent nightmares is controversial. Cortical oscillatory activity in REM sleep is largely modulated by phasic and tonic REM periods and seems to be linked to different functions and dysfunctions of REM sleep. Here, we examined cortical activity and functional synchronization in frequent nightmare recallers and healthy controls, during phasic and tonic REM. Methods Frequent nightmare recallers (N = 22) and healthy controls (N = 22) matched for high dream recall spent two nights in the laboratory. Phasic and tonic REM periods from the second nights’ recordings were selected to examine differences in EEG spectral power and weighted phase lag index (WPLI) across groups and REM states. Results Phasic REM showed increased power and synchronization in delta and gamma frequency bands, whereas tonic REM featured increased power and synchronization in the alpha and beta bands. In the theta band, power was higher during tonic, and synchronization was higher during phasic REM sleep. No differences across nightmare and control participants or patterns representing interactions between the groups and REM microstates emerged. Conclusions Our findings do not support the idea that abnormal REM sleep power and synchronization play a role in the pathophysiology of frequent nightmares. Altered REM sleep in nightmare disorder could have been confounded with comorbid pathologies and increased dream recall, or might be linked to more specific state factors (nightmare episodes). |
| Databáze: | OpenAIRE |
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