Study of Tree-sparrow (Passer montanus) as Natural Spreader of H5N1 Virus
| Autor: | Yusuke Takahara, Retno Asih Setyoningrum, Edith Frederika Puruhito, Resti Yudhawati, Hak Hotta, Aldise Mareta Nastri, Emmanuel Djoko Poetranto, Landia Setiawati, Adhitya Yoppy Ro Candra, Anna Lystia Poetranto, Laksmi Wulandari, Yasuko Mori, Kazufumi Shimizu |
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| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
animal structures Chemistry(all) viruses Virulence sparrow medicine.disease_cause Virus Incubation period 03 medical and health sciences biology.animal medicine H5N1 virus Sparrow biology Inoculation General Medicine biology.organism_classification Virology Influenza A virus subtype H5N1 030104 developmental biology embryonic structures Chemical Engineering(all) backyard hicken spreading Passer |
| Zdroj: | Procedia Chemistry. 18:205-212 |
| ISSN: | 1876-6196 |
| DOI: | 10.1016/j.proche.2016.01.032 |
| Popis: | To understand sparrow‘s ability in spreading H5N1 avian influenza virus, especially compared to backyard chicken, we performed an experimental infection study. Nine sparrows and backyard chickens were inoculated with H5N1 viruses isolated from sparrow and chicken. We observed the incubation period, clinical signs, and time of death after the exposure. We also carried out pathological anatomy and examined any histopathologyical changes. The results indicate that sparrows are more resistant to the H5N1 virus infection than chicken. The striking organ changes of sparrows died because of the virus infection were lungs and brains haemorrhage. Lung damage seemed to be the main cause of the chicken's death. Neuronal necrosis and gliosis seemed to cause the torticollis of sparrow. The H5N1 virus isolated from sparrow that was more virulent against sparrow than the virus isolated from chicken indicate the occurrence of sparrow's adaptation with the sparrow virus. Based on the longer incubation period and later time of death of sparrows after the virus infection than of chickens, and their ability to fly, we concluded that ability of sparrow to spread H5N1 virus was higher than that of backyard chicken. |
| Databáze: | OpenAIRE |
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