Retrospective allergy diagnosis of lysteriosis and lysteria carrying in animals

Autor: Natalia A. Askhatova, Elena Y. Mikryukova, Azat M. Alimov, Nadiya R. Kasanova
Rok vydání: 2020
Předmět:
Zdroj: BIO Web of Conferences, Vol 27, p 00054 (2020)
ISSN: 2117-4458
DOI: 10.1051/bioconf/20202700054
Popis: Experimental infections of guinea pigs and rabbits with a sublethal dose of L. monocytogenes pathogen caused an allergic reaction in the form of delayed-type hypersensitivity (DTHS), which was detected by an intradermal allergy test with a Listeriose allergen. The status of DTHS in guinea pigs and rabbits was recorded for a longer time as compared to specific antibodies. A positive allergic reaction correlated with listeria, which was confirmed by the isolation of a Listeria culture 6 months after infection of rabbits with a virulent Listeria strain. The research findings showed that an intradermal allergy test with a developed Listeria allergen allows a retrospective diagnosis of Listeriosis and Listeria carrying. A specific feature of Listeria allergen was established through an intradermal provocative test in animals sensitized by heterogeneous microorganisms (Salmonella and E. coli).
Databáze: OpenAIRE