Human rRNA Gene Clusters Are Recombinational Hotspots in Cancer
| Autor: | Jeffrey A. Moscow, H. David Vargas, Susanne M. Arnold, Jon S. Hourigan, Andrew J. Pierce, Michael W. Killen, Erica P. Williamson, Dawn M. Stults |
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| Rok vydání: | 2009 |
| Předmět: |
Adult
Genome instability Cancer Research Lung Neoplasms Adenocarcinoma Biology DNA Ribosomal Genomic Instability chemistry.chemical_compound Gene cluster Humans Child Gene Ribosomal DNA Recombination Genetic Genetics Leukemia Genes rRNA Ribosomal RNA Oncology chemistry Multigene Family Carcinoma Squamous Cell Human genome Colorectal Neoplasms Homologous recombination DNA |
| Zdroj: | Cancer Research. 69:9096-9104 |
| ISSN: | 1538-7445 0008-5472 |
| Popis: | The gene that produces the precursor RNA transcript to the three largest structural rRNA molecules (rDNA) is present in multiple copies and organized into gene clusters. The 10 human rDNA clusters represent |
| Databáze: | OpenAIRE |
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