C1q nephropathy in a patient with Gitelman syndrome
| Autor: | José Luis Lerma Márquez, Pedro Garcia-Cosmes, Pilar Fraile Gómez, María Asunción Gómez Muñoz, Consolación Rosado Rubio |
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| Rok vydání: | 2011 |
| Předmět: |
Transplantation
Pathology medicine.medical_specialty Lupus erythematosus Systemic lupus erythematosus Discoid lupus erythematosus medicine.diagnostic_test II. Clinical Reports nephrotic syndrome business.industry Case Reports Gitelman syndrome urologic and male genital diseases medicine.disease Bartter syndrome Dermatology C1q nephropathy Bartter's syndrome Nephrology medicine Renal biopsy business Nephrotic syndrome |
| Zdroj: | NDT Plus |
| ISSN: | 2048-8513 2048-8505 |
| DOI: | 10.1093/ndtplus/sfr097 |
| Popis: | Bartter syndrome can manifest in three different forms and is rarely concomitant with glomerular nephropathies. However, this association is more frequently observed in children. We report the case of a 50-year-old woman with Gitelman syndrome for the past 30 years who also had a nephrotic syndrome of recent appearance. Her renal biopsy revealed hyperplasia of the juxtaglomerular apparatus and mesangial deposits of C1q, with no clinical or serological evidence of systemic erythematous lupus. We have not found any reports of instances of association of Gitelman syndrome and nephrotic syndrome arising from C1q nephropathy in adult patients. Our case suggests the possible existence of an association between hypokalaemic tubular nephropathies and glomerular nephropathies that may cause nephrotic syndrome. |
| Databáze: | OpenAIRE |
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