Primary squamous cell carcinoma of the breast: A rare case report

Autor: Rosabel Lobo Alvarez, Jose Luis Lopez Guerra, Raquel Martin Hernandez, Stefania Carbone, Asuncion Almenar Gil, Hugo Marsiglia, Annalisa Lamacchia
Jazyk: angličtina
Předmět:
Zdroj: Reports of Practical Oncology & Radiotherapy. (6):363-366
ISSN: 1507-1367
DOI: 10.1016/j.rpor.2012.07.004
Popis: BackgroundSquamous cells are normally not found inside the breast. Therefore, a primary squamous cell carcinoma of the breast is an exceptional phenomenon and the management of this type of disease is still debated.AimClinical outcome assessment of a patient with squamous cell carcinoma of the breast.Materials and methodsWe report a case of primary squamous cell carcinoma of the breast (T1cN0M0) in a 51-years-old woman who underwent breast conserving surgery plus adjuvant chemotherapy and radiation therapy (RT).ResultsWith a follow up of 43 months, the patient is alive with no evidence of local or distant recurrence. The patient had Grade 2 acute skin toxicity. No late skin or respiratory toxicity was observed.ConclusionsPure primary squamous cell carcinoma of the breast is a rare and aggressive disease, often treatment-refractory. Our case shows that the addition of RT after breast conserving surgery, allows to achieve a high local control without adding severe toxicity. A multidisciplinary approach seems to be the optimal management for early stages in this rare disease.
Databáze: OpenAIRE