Suicide-attempters having immunoglobulin G with affinity for dopamine in cerebrospinal fluid
| Autor: | Jonas Bergquist, Lil Träskman-Bendz, Mats Lindström, Rolf Ekman |
|---|---|
| Rok vydání: | 2002 |
| Předmět: |
Adult
Male Dopamine Suicide Attempted medicine.disease_cause Immunoglobulin G Statistics Nonparametric Autoimmunity chemistry.chemical_compound Cerebrospinal fluid Monoaminergic medicine Humans Pharmacology (medical) Neurotransmitter Biological Psychiatry Aged Pharmacology biology Dopaminergic Middle Aged Psychiatry and Mental health Monoamine neurotransmitter Neurology chemistry Immunology biology.protein Female Neurology (clinical) Binding Sites Antibody Psychology medicine.drug |
| Zdroj: | European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. 12(2) |
| ISSN: | 0924-977X |
| Popis: | Altered immunological functions and changes in the monoaminergic neurotransmitter systems are two important observations made previously in the study of possible etiological and pathophysiological factors for psychiatric disorders. In search of tentative autoimmune mechanisms involved in these disorders we studied the presence of immunoglobulin G (DA-IgG) with affinity for the monoamine dopamine (DA) in cerebrospinal fluid (CSF) using ELISA. In CSF from 49 suicide attempters the titer of DA-IgG was significantly higher (P |
| Databáze: | OpenAIRE |
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