Analysis of factors associated with low peripheral blood progenitor cell collection in normal donors

Autor:	J Petit, Cristina Arbona, Felipe de Arriba, Carmen Martínez, Andrés Insunza, David P. Serrano, Isabel Sanjuan, Ildefonso Espigado, Miguel A. Sanz, R Arrieta, María Jesús Pascual, Joan Bargay, Concha Zamora, Miguel Angel Diaz, Dobleta Martínez, Luis Benlloch, Salut Brunet, Amparo Verdeguer, Javier de la Serna, Adrian Alegre, Javier de la Rubia, Consuelo del Cañizo
Rok vydání:	2002
Předmět:	Adult Male medicine.medical_specialty Multivariate analysis Adolescent Filgrastim Immunology CD34 Antigens CD34 Gastroenterology Blood cell Basal (phylogenetics) Sex Factors Bone Marrow Internal medicine Granulocyte Colony-Stimulating Factor medicine Immunology and Allergy Humans Progenitor cell Child Aged Univariate analysis Dose-Response Relationship Drug business.industry Body Weight Age Factors Hematology Middle Aged Hematopoietic Stem Cells Peripheral blood Hematopoietic Stem Cell Mobilization Recombinant Proteins Blood Cell Count Apheresis medicine.anatomical_structure Child Preschool Multivariate Analysis Female business
Zdroj:	Transfusion. 42(1)
ISSN:	0041-1132
Popis:	BACKGROUND: Predictive factors of the response to rHuG–CSF in normal donors have not been extensively studied. STUDY DESIGN AND METHODS: We analyzed factors influencing CD34+ cell yield in the 1st day of collection in 261 healthy donors from the Spanish National Donor Registry. The median age was 38 years (range, 2-72). The median dose of rHuG–CSF was 10 μg per kg per day (range, 5-20) over 4 days. In 103 donors (40%)
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c59ee3a75809a3be0f4c5fa87b0f8fb https://pubmed.ncbi.nlm.nih.gov/11896306 Zobrazit plný text záznamu Plný text