Nonsecretory multiple myeloma
| Autor: | Prakash Kanse, Seshikanth Middela |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2009 |
| Předmět: |
Pathology
medicine.medical_specialty business.industry Case Report Disease medicine.disease bone tumor Lesion lcsh:RD701-811 medicine.anatomical_structure Lytic cycle lcsh:Orthopedic surgery Multiple myeloma Orthopedic surgery Medicine Orthopedics and Sports Medicine non secretory medicine.symptom Differential diagnosis business Pathological B cell |
| Zdroj: | Indian Journal of Orthopaedics, Vol 43, Iss 4, Pp 408-411 (2009) Indian Journal of Orthopaedics |
| ISSN: | 1998-3727 0019-5413 |
| Popis: | Multiple myeloma is characterized by clonal proliferation of plasma cells usually of the B cell type. The skeletal manifestations are usually osteolytic lesions whose differential diagnosis includes primary and secondary bone tumor. This tumor is characterized by the presence of abnormal paraprotein 8 in blood and urine. However, one to five per cent of the cases do not have any protein. Hence they are termed nonsecretory. It often poses a diagnostic dilemma when it is presented to orthopedic surgeons with no clear features of the disease. Our case report exemplifies such a diagnostic dilemma. A high index of suspicion must be borne in mind when excluding multiple myeloma as a cause of pain, pathological fracture or lytic lesion. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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