Fixed dose 4-factor prothrombin complex concentrate for bleeding caused by long acting anticoagulant rodenticides
| Autor: | Richard J. Doyle, Kevin Kolman, Zane Elfessi |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Male
Pediatrics medicine.medical_specialty Vitamin K Difenacoum Synthetic Drugs medicine.drug_class Hemorrhage 030204 cardiovascular system & hematology Fixed dose 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine medicine Humans Drug Dosage Calculations Aged Illicit Drugs business.industry Anticoagulant Anticoagulants Rodenticides 030208 emergency & critical care medicine 4-Hydroxycoumarins General Medicine Blood Coagulation Disorders Prothrombin complex concentrate Blood Coagulation Factors Abdominal Pain Treatment Outcome Long acting Coagulation Rodenticide poisoning chemistry Emergency Medicine Drug Contamination business Brodifacoum medicine.drug |
| Zdroj: | The American Journal of Emergency Medicine. 36:1922.e3-1922.e4 |
| ISSN: | 0735-6757 |
| DOI: | 10.1016/j.ajem.2018.06.040 |
| Popis: | Acute, unintentional drug-related poisonings lead to an estimated 418,313 ED visits in 2014, according to the latest statistics from the Center for Disease Control and Prevention. While most of these were opiate-related poisonings, anticoagulant rodenticides were the most common cause of rodenticide-related poisoning in the United States. Many clinical syndromes and treatment algorithms have been described for patients with anticoagulant rodenticide poisoning. We report a case of an acute ingestion of two anticoagulant rodenticides and successful reversal of coagulation parameters using 4-factor prothrombin complex concentrate in a fixed-dose approach. |
| Databáze: | OpenAIRE |
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