Groin wound infection after vascular exposure (GIVE) multicentre cohort study

Autor: Emily Kirkham, Lucy Green, James Olivier, Michelle Cronin, Calvin Eng, Jonathan Nicholls, Ruth A. Benson, Arsalan Wafi, Tariq Al-Samarneh, Samuel Debono, Dafydd Locker, Khalid Bashar, Hazem Ahmed, David C. Bosanquet, Ahmed Elbasty, George Davey Smith, Gareth Harrison, Amy Stimpson, Madhu Rangaraju, Ghazaleh Mohammadi-Zaniani, Benjamin Patterson, Paul Moxey, P.W. Stather, Fernando Picazo, Sarah Onida, Nicholas Platt, Timothy Beckitt, Matthew Brown, Ala Khaled, Hannah Burton, Faris Saleh, Louise Hitchman, Ahmed Msherghi, Panagiota Birmpili, Keith Hussey, Joseph Shalhoub, Mohamed Altabal, Tom Hardy, Ian Barry, Devender Mittapalli, Graeme K. Ambler, George Dovell, Daniel U. Rodriguez, David Cooper, Bethany Wardle, Trixie Yap, Kerry Burke, Ryan Preece, Bridget Egan, Ahmed Hassanin, Kamran Mohiuddin, Tristan R A Lane, James Ackah, David Milgrom, Ankur Thapar, Nikesh Dattani, Danielle Lowry, Elaine Townsend, Rachel Falconer, Tryfon Vanias, H M Moore, Sandhir Kandola, Andrew Cowan, Russell Jamieson, Iain Roy, Muhammed Elhadi, Sean Tierney, Toby Richards, Olivia McBride, Simon Neequaye, Salil Korambayil, Luke Hopkins, Shaneel Patel, Nishath Altaf, Owain Fisher, Tasleem Akhtar, Emily Boyle, Rachel Sam, Alexander Crichton, Lewis Meecham, Aminder A. Singh, Kamil Naidoo, Athanasios Saratzis, Mohedin Arifi, Francesca Guest, Enrico Mancuso, Ella Schofield, James Forsyth, Brenig Llwyd Gwilym, Tom Wallace, Ahmed Shalan, Thomas Aherne, Andrew Duncan, Michael Rocker, Andrew J. Batchelder, Craig Forrest, Adnan Bajwa, Olivia Grant, Ummul Contractor, Huw Ob Davies, Aled Jones, Konstantinos Tigkiropoulos, Annie Clothier, Maciej T. Juszczak, Thomas Wilson, Asif Mahmood, Claire Perrott, Robert J. Hinchliffe, Abdulmunem Althini, Sandip Nandhra, Helen Suttenwood, Hannah Danbury, Kishore Sieunarine, Ahmed Elhadi, Ciaran Brennan, Katherine Hurst, Natasha Chinai, Rachael O. Forsythe
Rok vydání: 2020
Předmět:
Zdroj: International Wound Journal
ISSN: 1742-481X
Popis: Background: Surgical site infections (SSIs) of groin wounds are a common and potentially preventable cause of morbidity, mortality and healthcare costs in vascular surgery. Our aim was to define the contemporaneous rate of groin SSIs, determine clinical sequelae, and identify risk factors for SSI. Method: An international multicentre prospective observational cohort study of consecutive patients undergoing groin incision for femoral vessel access in vascular surgery was undertaken over 3 months, follow up was 90 days. The primary outcome was incidence of groin wound SSI. Results: 1337 groin incisions (1039 patients) from 37 centres were included. 115 groin incisions (8.6%) developed SSI, of which 62 (4.6%) were superficial. Patients who developed an SSI had a significantly longer length of hospital stay (6 vs 5 days, p=0.005), a significantly higher rate of post-operative acute kidney injury (19.6% vs 11.7%, p=0.018), with no significant difference in 90-day mortality. Female sex, Body Mass Index≥30kg/m2, ischaemic heart disease, aqueous betadine skin preparation, bypass/patch use (vein, xenograft or prosthetic) and increased operative time were independent predictors of SSI. Conclusion: Groin infections which are clinically apparent to the treating vascular unit are frequent and their development carries significant clinical sequelae. Risk factors include modifiable and non-modifiable variables.
Databáze: OpenAIRE