Omega-3 Supplementation for Psychotic Mania and Comorbid Anxiety in Children
| Autor: | Andrea S. Young, L. Eugene Arnold, Mary A. Fristad, Anthony T. Vesco, Barbara L. Gracious, Jennifer M. Lehmann |
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| Rok vydání: | 2015 |
| Předmět: |
medicine.medical_specialty
Psychosis Generalized anxiety disorder Bipolar Disorder Adolescent media_common.quotation_subject MEDLINE Fatty Acids Omega-3 medicine Humans Pharmacology (medical) Girl Bipolar disorder Psychiatry Child media_common Mood Disorders Original Articles medicine.disease Anxiety Disorders Psychiatry and Mental health Mood disorders Pediatrics Perinatology and Child Health Dietary Supplements Anxiety Female medicine.symptom Psychology Mania Clinical psychology |
| Zdroj: | Journal of child and adolescent psychopharmacology. 25(7) |
| ISSN: | 1557-8992 |
| Popis: | Therapeutic benefits of omega-3 fatty acids (Ω3) for mood disorders, psychosis, and anxiety have been reported in the literature. The purpose of the present article is to provide a literature review of Ω3 supplementation for affective disorders and to illustrate the benefits of Ω3 with a case presentation of a young girl with a history of bipolar disorder-type 1 with psychotic features and generalized anxiety disorder.Reviewed literature includes treatment studies of the impact of Ω3 on child mood disorders supplemented by review of meta-analyses within the adult mood disorders literature. The subject of this case report participated in 11 in-depth diagnostic and functional assessments over 5 years as part of an unrelated study. Three years were presupplementation and 2 years were with supplementation with no other medication changes, thus making a naturalistic multiple-baseline single-subject experiment.Augmentation over a 2 year period was notable for clinically significant and sustained improvement in depressive, manic, and psychotic symptoms.Ω3 supplementation may be a safe, adjunct intervention for treating bipolar disorder in children and adolescents, even in the presence of psychotic and anxious features. The 2 year follow-up in this case offers hope of an accumulating and enduring benefit. Further research into mechanisms of Ω3 action and of combination treatment with other well-known interventions for mood disorders would be beneficial. |
| Databáze: | OpenAIRE |
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