Endoscopic Papillary Large Balloon Dilation for Treatment of Large Bile Duct Stones Does Not Increase the Risk of Post-procedure Pancreatitis
| Autor: | Kook Hyun Kim, Tae Nyeun Kim, Jun Suk Park |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Adult
Male medicine.medical_specialty Physiology Post-Procedure Gallstones digestive system Common duct stones Sphincterotomy Endoscopic Young Adult Postoperative Complications Internal medicine medicine Humans Aged Retrospective Studies Aged 80 and over Cholangiopancreatography Endoscopic Retrograde Bile duct business.industry Significant difference Gastroenterology Retrospective cohort study Middle Aged Hepatology medicine.disease digestive system diseases Surgery surgical procedures operative medicine.anatomical_structure Pancreatitis Balloon dilation Female Radiology business |
| Zdroj: | Digestive Diseases and Sciences. 59:3092-3098 |
| ISSN: | 1573-2568 0163-2116 |
| DOI: | 10.1007/s10620-014-3259-3 |
| Popis: | Endoscopic sphincterotomy (ES) and endoscopic papillary large balloon dilation (EPLBD) are well-known procedures for the treatment of common duct stones. There was no statistically significant difference in post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis rates between ES and EPLBD in most studies. The aims of this study were to evaluate whether EPLBD increases the risk of post-ERCP pancreatitis and to identify the risk factors influencing post-ERCP pancreatitis.A review of 341 patients who underwent ERCP for treatment of common duct stones larger than 1 cm in diameter from January 2006 to December 2011 was conducted retrospectively. Patients were divided into three groups: ES group (n = 207), EPLBD + ES group (n = 99), and EPLBD with previous history of ES group (n = 35).Of 341 patients, overall incidence of post-ERCP pancreatitis was 2.6% (n = 9). Incidence of post-ERCP pancreatitis was 3.4, 2.0, and 0% in the ES group, EPLBD + ES group, and EPLBD with previous history of ES group, respectively. No significant difference in the incidence of post-ERCP pancreatitis was observed among the three groups (p = 0.47). Endoscopic biliary stenting was the independent risk factor for pancreatitis according to univariate (p = 0.046) and multivariate analyses (p = 0.036, OR 4.211, 95% CI 1.095-16.199). Age, sex, stone size, mechanical lithotripsy, common bile duct diameter, balloon size, and duration of balloon dilation were not significantly related to post-ERCP pancreatitis.EPLBD with antecedent limited ES or previous ES state does not increase the risk of post-ERCP pancreatitis in patients with large bile duct stones. Endoscopic biliary stenting seems to be the independent risk factor of post-ERCP pancreatitis. |
| Databáze: | OpenAIRE |
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