Soft tissue regeneration using leukocyte-platelet rich fibrin after exeresis of hyperplastic gingival lesions: Two case reports
| Autor: | B. Dell’Angelo, A.E. di Lauro, G.A. Iannaccone, D. Abbate, Gilberto Sammartino, Fabio Scotto |
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| Přispěvatelé: | DI LAURO, ALESSANDRO ESPEDITO, Abbate, D., Dell'Angelo, B., Iannaccone, G. A., Scotto, F., Sammartino, Gilberto |
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
Blood Platelets
Adult Male medicine.medical_specialty Pathology Epulis Case Report Fibrin Surgical oncology Granuloma Giant Cell Soft tissue healing Radiography Panoramic Leukocytes Humans Medicine Regeneration Platelet Aged Medicine(all) biology business.industry Regeneration (biology) Medicine (all) Soft tissue General Medicine Leukocyte medicine.disease Platelet-rich fibrin Surgery Epuli Hyperplastic gingival lesion Hyperplastic gingival lesions biology.protein Tissue healing Blood Platelet Female business PRF Human |
| Zdroj: | Journal of Medical Case Reports |
| Popis: | Introduction The Leukocyte-PRF (Leukocyte-Platelet Rich Fibrin) belongs to a second generation of platelet concentrates which doesn’t need a biochemical blood manipulation. It is used for tissue healing and regeneration in periodontal and oral-maxillofacial surgery. We report two cases of hyperplastic gingival lesions treated by exeresis and application of PRF membranes in order to improve and accelerate tissue healing. Case Presentation Two patients (one Caucasian female, 78-year-old, and one Caucasian male, 30-year-old) were treated for hyperplastic gingival lesions. They underwent to exeresis of lesions and application of PRF membranes. Tissue healing was clinically evaluated after one, three, seven, fourteen and thirty post-operative days. No recurrences were observed after two years of semiannual follow up. Conclusion We obtained rapid and good healing of soft tissues probably due to the elevated content of leukocytes, platelets and growth factors in the leukocyte-platelet rich fibrin. According to our results we suggest L-PRF employment for wounds covering after exeresis of oral neoformations such as hyperplastic gingival lesions. |
| Databáze: | OpenAIRE |
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