Seroreversion of treponemal tests in infants meeting canadian surveillance criteria for confirmed early congenital syphilis
Autor: | Ameeta E. Singh, Bonita E. Lee, Joan L. Robinson, Jennifer Gratrix, Barbara Anderson, Penny Parker, Joshua Bergman, Tamara Guenette, Sabrina Plitt |
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Rok vydání: | 2012 |
Předmět: |
Microbiology (medical)
Pediatrics medicine.medical_specialty Canada Rapid plasma reagin Serology Pregnancy Chart review medicine Humans Serologic Tests medicine.diagnostic_test business.industry Syphilis Congenital Age Factors Infant Newborn Infant Delayed treatment medicine.disease Infectious Diseases Congenital syphilis Child Preschool Pediatrics Perinatology and Child Health Syphilis Female business |
Zdroj: | The Pediatric infectious disease journal. 32(3) |
ISSN: | 1532-0987 |
Popis: | Background Few data exist on the serologic outcome of treponemal tests in congenital syphilis. Methods A chart review was conducted on all confirmed early congenital syphilis cases in Edmonton, Canada, from 2005-2010. Results Of the 16 cases identified, 11 (69%) infants seroreverted their treponemal tests by 18 months. Cases that did not serorevert their treponemal tests were statistically more likely to have delayed treatment and to have higher maternal rapid plasma reagin titers at birth. Conclusions Our data suggest that the majority of early congenital syphilis cases will serorevert their treponemal tests by 18 months. |
Databáze: | OpenAIRE |
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