Intervertebral disk: normal age-related changes in MR signal intensity
| Autor: | L A Sether, M E Fischer, Victor M. Haughton, Shiwei Yu |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Adult
Aging Adolescent Lumbar Nuclear magnetic resonance Body Water Age related medicine Humans Radiology Nuclear Medicine and imaging Child Intervertebral Disc Aged Lumbar Vertebrae medicine.diagnostic_test business.industry Echo time Infant Newborn Infant Magnetic resonance imaging Middle Aged Magnetic Resonance Imaging Sagittal plane Intervertebral disk medicine.anatomical_structure Repetition Time Child Preschool Proteoglycans Autopsy Collagen Signal intensity business |
| Zdroj: | Radiology. 177(2) |
| ISSN: | 0033-8419 |
| Popis: | The effect of age on the signal intensity of normal lumbar intervertebral disks was studied. Twenty-seven cadavers ranging in age from newborn to 79 years were studied with use of a 1.5-T magnetic resonance (MR) imager within 48 hours of death. The signal intensity in the central area of the disk was measured on a sagittal image obtained with a long repetition time (TR) and a long echo time (TE) and correlated to the age. A significant correlation between the decrease in signal intensity and age was found, although signal intensity changed less than 6% in 80 years. The decrease in signal intensity is concomitant with decreases in water and glycosaminoglycans and increases in collagen in the disk. |
| Databáze: | OpenAIRE |
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