Diets deficient in selenium and vitamin E affect plasma lipoprotein and apolipoprotein concentrations in the rat
| Autor: | Fatiha Nassir, E. Gueux, Yves Rayssiguier, A. Mazur, Pascal Grolier, Corinne Moundras, Edmond Rock, Jacques Bellanger |
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| Rok vydání: | 1996 |
| Předmět: |
Male
Vitamin medicine.medical_specialty Apolipoprotein B Lipoproteins medicine.medical_treatment Medicine (miscellaneous) Selenium chemistry.chemical_compound Apolipoproteins E Internal medicine Blood plasma medicine Animals Vitamin E Deficiency Rats Wistar Nutrition and Dietetics biology Chemistry Cholesterol Vitamin E Metabolism Rats Apolipoproteins Endocrinology biology.protein lipids (amino acids peptides and proteins) Vitamin E deficiency Lipoprotein |
| Zdroj: | British Journal of Nutrition. 76:899-907 |
| ISSN: | 1475-2662 0007-1145 |
| DOI: | 10.1079/bjn19960096 |
| Popis: | The present study examined the effects of Se, vitamin E and combined Se and vitamin E deficiencies in rats on plasma lipid, Lipoprotein and apolipoprotein (apo) concentrations. Deficiencies were induced by feeding rats the respective diets for 6 weeks. The study shows that Se deficiency results in increased concentrations of plasma cholesterol and apo E. Both could be explained by an increase in the HDL1 fraction. Vitamin E deficiency alone had no significant effect on plasma lipid, lipoprotein and apo concentrations. Se deficiency in combination with vitamin E deficiency leads to an increase in plasma LDL and apo B concentrations. These results point to the need for further investigations on the mechanism by which Se deficiency affects lipoprotein metabolism. |
| Databáze: | OpenAIRE |
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