Columnar epithelium morphology after esophagectomy: clinical insight into the development of Barrett’s esophagus
Autor: | Yu Ohkura, Daisuke Kikuchi, Yugo Suzuki, Yoshio Hoshihara, Masaki Ueno, Toshiro Iizuka |
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Rok vydání: | 2020 |
Předmět: |
Male
medicine.medical_specialty medicine.medical_treatment Anastomosis Gastroenterology Epithelium Duodenogastric Reflux Gastric Acid Barrett Esophagus 03 medical and health sciences 0302 clinical medicine Internal medicine Humans Medicine Endoscopy Digestive System Reflux esophagitis Esophagus Esophagitis Peptic Aged Retrospective Studies Aged 80 and over business.industry Anastomosis Surgical Reflux Middle Aged Plastic Surgery Procedures medicine.disease digestive system diseases Esophagectomy medicine.anatomical_structure Case-Control Studies 030220 oncology & carcinogenesis Barrett's esophagus Multivariate Analysis Gastric acid Female 030211 gastroenterology & hepatology business |
Zdroj: | Esophagus. 17:392-398 |
ISSN: | 1612-9067 1612-9059 |
DOI: | 10.1007/s10388-020-00742-9 |
Popis: | The presence of Barrett’s mucosa in the esophageal remnant is a result of post-esophagectomy anastomotic site exposure to gastric acid and is regarded as a human model of Barrett’s esophagus onset. Here, we attempted to clarify the relationship between duodenogastric reflux and formation of columnar epithelium by following the changes over time after esophagectomy. A total of 96 patients underwent esophagectomy due to superficial cancer from April 2000 to March 2018 were included in this study. Cases were divided into two groups according to the reconstruction technique after esophagectomy as either the gastric pull-up (Ga) group and ileocolonic interposition (Ic) group. Previously obtained endoscopic pictures of the cases were reviewed retrospectively and chronologically. There were 24 cases of columnar epithelium in the Ga group (42%) and 1 in the Ic group (2.6%) (P |
Databáze: | OpenAIRE |
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