The effects of galactooligosaccharide on systemic and mucosal immune response, growth performance and appetite related gene transcript in goldfish (Carassius auratus gibelio)
Autor: | Ali Shabani, Seyed Hossein Hoseinifar, Hamed Kolangi Miandare, Shoeib Farvardin, Seyyede Sanaz Ramezanpour |
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Rok vydání: | 2016 |
Předmět: |
0301 basic medicine
medicine.medical_specialty Globulin Transcription Genetic medicine.medical_treatment media_common.quotation_subject Appetite Oligosaccharides Aquatic Science 03 medical and health sciences chemistry.chemical_compound Random Allocation Immune system Internal medicine Goldfish medicine Environmental Chemistry Animals Immunity Mucosal media_common biology Galactooligosaccharide Prebiotic 04 agricultural and veterinary sciences General Medicine Animal Feed Immunity Innate Diet 030104 developmental biology Endocrinology chemistry Dietary Supplements 040102 fisheries biology.protein 0401 agriculture forestry and fisheries Alkaline phosphatase Ghrelin Lysozyme |
Zdroj: | Fishshellfish immunology. 55 |
ISSN: | 1095-9947 |
Popis: | The present study investigates the effects of supplementation of goldfish (Carassius auratus gibelio) diet with galactooligosaccharide (GOS) on serum immune response, mucosal immune parameters as well as appetite-related (Ghrelin) and immune-related (TNF-1α and TNF-2α) genes expression. One hundred and eighty fish with an average weight of 4.88 ± 0.28 g were stocked in twelve 500-L fiberglass tank assigned to four treatments repeated in triplicates. Fish were fed on experimental diets contain 0.5, 1 and 2% GOS for 6 weeks. Supplementation of diet with GOS had no remarkable effect on goldfish growth performance (P > 0.05). Evaluation of serum innate immune parameters revealed that supplementation of diet with GOS significantly elevated total protein, Albumin, Globulins, Lysozyme and Alkaline phosphatase activity as well as agglutination compared to control group in a dose dependent manner (P |
Databáze: | OpenAIRE |
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