Posttransplant diabetes mellitus: incidence and risk factors
Autor: | M. Lessan-Pezeshki, Maryam Rahbar, Mohammad-Reza Abbasi, Sima Maziar, M R Khatami, Farrokhlagha Ahmadi, Mitra Mahdavi-Mazdeh, Sepideh Seifi |
---|---|
Rok vydání: | 2009 |
Předmět: |
Adult
Blood Glucose Male medicine.medical_specialty medicine.medical_treatment Blood Pressure Peritoneal dialysis Blood Urea Nitrogen Body Mass Index Young Adult Renal Dialysis Risk Factors Internal medicine medicine Diabetes Mellitus Humans Renal replacement therapy Kidney transplantation Triglycerides Transplantation business.industry Incidence (epidemiology) Incidence Smoking Middle Aged medicine.disease Kidney Transplantation Surgery Renal Replacement Therapy Blood pressure Hypertension Kidney Failure Chronic Female Complication business Body mass index Peritoneal Dialysis Follow-Up Studies |
Zdroj: | Transplantation proceedings. 41(7) |
ISSN: | 1873-2623 |
Popis: | Objective. Posttransplant diabetes mellitus (PTDM) is a common and serious complication of renal transplantation. Estimates of the incidence of PTDM after renal transplantation vary between 2% and 54%. The aim of the present study was to evaluate the incidence and risk factors for PTDM among our renal transplant patients. Patients and Methods. In this study we evaluated 121 nondiabetic patients with end-stage renal disease (ESRD) who underwent kidney transplantation for the first time at our centers since 2005. All patients received the same protocol of immunosuppressive therapy. PTDM was defined according to the clinical practice recommendations of the American Diabetes Association. Results. At 12 months following renal transplantation, 9.9% of patients developed PTDM. Patients with PTDM were significantly older (P .013) and had higher body mass index (P .001). There were significant differences (P .05) between PTDM and non-PTDM patients with respect to systolic blood pressure, serum triglycerides (TG), peritoneal dialysis as renal replacement therapy before transplantation, and duration of pretransplant dialysis therapy. Upon multivariate analysis, serum TG, systolic blood pressure, and body mass index were associated with PTDM (P .05). Conclusions. The incidence at 12 months of PTDM among our renal transplant recipients was 9.9%. The most important factors associated with PTDM were serum TG, systolic blood pressure, and body mass index. |
Databáze: | OpenAIRE |
Externí odkaz: |