Electrospray ionization gas-phase electrophoresis under ambient conditions and it's potential or high-speed separations
| Autor: | Milton L. Lee, D. C. Collins |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
Electrophoresis
Desorption electrospray ionization Electrospray Chemical ionization Chromatography Diazepam Time Factors Alprazolam Chemistry Herbicides Oxazepam Triazines Electrospray ionization Analytical chemistry Equipment Design Biochemistry Volumetric flow rate Ion Anti-Anxiety Agents Ionization Combinatorial Chemistry Techniques Prazepam Nitrazepam |
| Zdroj: | Fresenius' journal of analytical chemistry. 369(3-4) |
| ISSN: | 0937-0633 |
| Popis: | A moderately high resolution nanoelectrospray ionization gas-phase electrophoresis instrument was constructed and evaluated for simple high-speed separations of several groups of compounds. The insertion of a plate containing a 1.6 cm diameter exit orifice, 2.5 cm from the location of electrospray, allowed ions to be created and desolvated under ambient conditions with minimal solvent contamination to the drift tube. Ion separation selectivity is discussed and shown to be slightly altered by changing the drift gas flow rate. Issues of using gas-phase electrophoresis as a high-speed separation technique are discussed. Gas-phase electrophoresis-spectra of selected benzodiazepines, triazine herbicides, and simple combinatorial chemistry libraries are demonstrated. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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