Impact of palliative treatment on survival in sinonasal malignancies
| Autor: | Wayne D. Hsueh, Julia Riccardi, Jean Anderson Eloy, Richard D Bavier, Nicole I Farber, Roman Povolotskiy |
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| Rok vydání: | 2019 |
| Předmět: |
Oncology
Male medicine.medical_specialty Palliative care Palliative Radiation Therapy Combination therapy Databases Factual Nasal Surgical Procedures Kaplan-Meier Estimate 03 medical and health sciences 0302 clinical medicine Internal medicine Immunology and Allergy Medicine Humans Stage (cooking) 030223 otorhinolaryngology Survival analysis Aged Neoplasm Staging Proportional Hazards Models business.industry Proportional hazards model Hazard ratio Palliative Care Cancer medicine.disease 030228 respiratory system Otorhinolaryngology Carcinoma Squamous Cell Female business Paranasal Sinus Neoplasms |
| Zdroj: | International forum of allergyrhinologyReferences. 9(12) |
| ISSN: | 2042-6984 |
| Popis: | BACKGROUND Although palliative care treatment modalities have been shown to improve functional outcomes and provide symptom alleviation in sinonasal cancer, its impact on survival still remains unclear. In this study we aimed to elicit the impact of different palliative therapy options on survival in a nationally representative sample of sinonasal cancer patients. METHODS National Cancer Database 2004-2015 data sets were queried for cases of primary sinonasal cancer (N = 380). Kaplan-Meier analysis was utilized to determine median overall survival (M-OS) and overall survival (OS) among the different treatment cohorts (pain management, palliative radiation therapy, palliative chemotherapy, palliative surgery, and combination therapy). Prognostic factors were elicited by comparing OS by log-rank tests and subsequent multivariate Cox regression analysis. RESULTS Of the total patients of sinonasal malignancy treated with palliative therapy, most were |
| Databáze: | OpenAIRE |
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