Anisotropy of the passive and active rat vagina under biaxial loading
| Autor: | Steven D. Abramowitch, Alyssa Huntington, Zaccaria Del Prete, Raffaella De Vita, Emanuele Rizzuto |
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| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Contraction (grammar)
030232 urology & nephrology Stimulation anisotropy mechanical properties contractility Potassium Chloride Contractility 03 medical and health sciences Standard anatomical position 0302 clinical medicine biomedical engineering medicine Animals Rats Long-Evans Anisotropy biaxial tests vagina 030219 obstetrics & reproductive medicine Chemistry Muscle Smooth Anatomy Electric Stimulation Rats Vaginal tissue medicine.anatomical_structure Rat Vagina Vagina Female Muscle Contraction |
| Popis: | Pelvic organ prolapse, the descent of the pelvic organs from their normal anatomical position, is a common condition among women that is associated with mechanical alterations of the vaginal wall. In order to characterize the complex mechanical behavior of the vagina, we performed planar biaxial tests of vaginal specimens in both the passive (relaxed) and active (contracted) states. Specimens were isolated from virgin, female Long-Evans rats (n = 16) and simultaneously stretched along the longitudinal direction (LD) and circumferential direction (CD) of the vagina. Tissue contraction was induced by electric field stimulation (EFS) at incrementally increasing values of stretch and, subsequently, by KCl. On average, the vagina was stiffer in the CD than in the LD (p |
| Databáze: | OpenAIRE |
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