Assisted Breathing with a Diaphragm Pacing System: A Systematic Review
| Autor: | Chae-Man Lim, Chae-min Shin, Ha-jin Tchoe, Hae-Won Shin, A-la Woo |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Diaphragm MEDLINE 030204 cardiovascular system & hematology law.invention 03 medical and health sciences 0302 clinical medicine Randomized controlled trial law Medicine Humans Amyotrophic lateral sclerosis Adverse effect Spinal cord injury Spinal Cord Injuries business.industry Respiration Amyotrophic Lateral Sclerosis General Medicine Prostheses and Implants medicine.disease Respiration Artificial spinal cord injury Diaphragm pacing Pulmonology & Critical Care Medicine Treatment Outcome Respiratory failure 030220 oncology & carcinogenesis Emergency medicine Original Article business electrical stimulation therapy Respiratory Insufficiency Cohort study |
| Zdroj: | Yonsei Medical Journal |
| ISSN: | 1976-2437 0513-5796 |
| Popis: | Purpose Patients with respiratory failure associated with neurological dysfunction often require mechanical ventilator support, which poses increased economic burden and ventilator-associated complications. A diaphragm pacing system (DPS) is an implanted device that provides respiratory support for such patients. In this systematic review, we reviewed the literature to assess the safety and efficacy of DPS for patients with respiratory failure resulting from amyotrophic lateral sclerosis (ALS) or cervical spinal cord injuries. Materials and methods The following databases were searched from July 10 to July 30, 2018: MEDLINE, EMBASE, Cochran library, KoreaMed, Research Information Sharing Service, Korean studies Information Service System, Korea Institute of Science and Technology Information, and Korean Medical database. The abstracts and full texts of the searched articles were reviewed by two reviewers. Results The search keywords generated 197 articles: two randomized controlled trials, two case-control studies, and one case report involving patients with ALS; one cohort study, one case-control study, and two case reports involving patients with cervical spine injury; and one case report involving patients with both conditions were included. The primary outcome was safety profile (complications and adverse event) and efficacy (overall survival and sleep improvement). Complications and adverse events were more common in patients with ALS and spinal cord injury receiving DPS than in controls. Efficacy outcomes were inconsistent across ALS studies. Conclusion Based on safety and efficacy results, we do not support using DPS to manage respiratory failure in patients with ALS or cervical spine injury. |
| Databáze: | OpenAIRE |
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